Zhou Wu (吴舟)

Research Fellow, The Roslin institute, UK.

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About me

I am currently a research fellow at the Roslin institute, University of Edinburgh, UK. My project is about the genomics of sparrow and the RNA-seq analysis on seasonality. I did my PhD in Wageningen University& Research, the Netherlands. My PhD project in WUR focused on functional genomics in chicken, especially genetic variants and haplotype diversity, including the genotype-phenotype mapping of chicken dwarfism, population genetics of human-mediated introgression, comparative genomics, and transcriptomics.

Avian genomics; Chicken dwarfism; bird genome and transcriptome; Bioinformatics; Population genomics; Ecology and environmental stress.

Research experience： Whole-genome sequence data, RNA-seq data,and genome editing techniques (CRISPR-Cas9).

My passion and interest are growing in bioinformatics to develop bioinformatic pipelines, understanding the function of the genome; using genomics to study the demographic history of domesticated populations; and how gene regulation in response to changing climate in free-living birds. I am a person full of curiosity, which makes me enthusiastic about new ideas. :metal:

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Highlights

  1. Identified a novel loss-of-function mutation in TMEM263 to be associated with dwarfism.

  2. Identified the genetic variants underlying dwarfism in Dutch indigenous chicken breeds. For the first time in avian species, discovered the widly recognized gene that is responsible for body size (HMGA2).

  3. Using haploytpe-based approch (rIBD) to identify the hybridization and selection history of small chicken populations.

  4. Generated the high-quality reference genome assembly for a free-living bird (Zonotrichia leucophrys).

Publications

(# denotes corresponding authors)

Education background